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Assisting the reactivation of guanidine hydrochloride-denatured aminoacylase by hydroxypropyl cyclodextrins
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RESULTS AND DISCUSSION Thermal and GndHCl-induced unfolded states All α-amylases investigated in this study consist of a monomeric structure with three domains
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49 nm)-the two predominant species at this low pH-the particles appear to be lying flat on the mica surface
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This is both natural and necessary, since data from kinetic experiments do just the same, but there is a danger in overlooking aspects of folding that rely essentially on the presence of many degrees of freedom
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The first just gives the large dimensionality of hypersphere, the second the flat diffusive landscape
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AN EXAMPLE: THREE-HELIX PROTEINSThe three-helix example illustrates our general conclusion that searches within diffusional subspaces in protein folding may be accelerated by local, but not necessarily native, interactions between sections of partially structured chain
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Chan's key rules--keep playing when you are winning, stop when you are losing, stay to an environment where you feel comfortable, take a vacation from poker when you need it (never try to win the money needed for a vacation from poker when you need one, that's a certain way to burnout), and discipline yourself to move back down to smaller tables when you're losing at big tables--are vital and should be taken to heart by all prospective professional poker players
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A significant main effect of competitiveness was also found such that high-competitive participants (M = 2
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* Burned--Discarded; what is done to the top card after the deck is cut so that players can't see its value
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Individual hands in a block were designated randomly as winning or losing
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Play was often made late into the night, and, most importantly, Wagenaar's players were playing with money that they had brought to the table
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In a similar way to models using expected values, models using expected utility weigh utilities by the probabilities of occurrence of the corresponding objective values and suggest that people make choices that maximize the expected utility
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