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However, since folding requires the formation of spatial, long-range contacts, local nonnative contacts have to he broken
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Molecular hinges in protein folding: The urea-denatured state of apomyoglobin
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The sample with the protein and the effectors was incubated for a minimum of 2 h at room temperature
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The modeled structure of the EIC^sup sc^ monomer differed from that of EIC^sup tt^ (11) only in a deletion in the loop between α-helix 4 and β-strand 5, which is part of neither the active center nor the dimerization surface
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COPDApoptotic cells are increased in the lungs of COPD patients (3,8) and in animal models of COPD
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MSDs above 61°CThe finding that MSDs of native HuBChE tend to be larger than those of soman-inhibited HuBChE starting ~3° below the denaturation temperature of native HuBChE (~64°C) is in line with results from several techniques indicating that denaturation increases atomic flexibility of proteins (17,51,52)
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Compaction of DNA was observed as a change in the conformation of DAPI-stained T4 DNA from a coil (Fig
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Atmospheric measurements were performed using 3-mm cuvettes
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The Θ^sub 222^(t) data show a rapid signal loss at any Gdm HCl concentration, indicating fast unfolding within the dead-time of the experiment (30 s), which precludes its quantitative analysis; the amplitude of this rapid phase increases with increasing denaturant concentration (Fig
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Repetitive T-jumps with DMPC complexes containing apoA-1, apoC-1, or apoA-2 show that the protein unfolding in the first jump is slower than that in consecutive jumps (Fig
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Exp Cell Res 1994:212:97-104
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A LOOK AT DISPARITIESThe percentage of women pharmacy faculty has increased from 30 percent of all pharmacy faculty in 1985, to 55 percent in 2002
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Jack of smarts: why the Internet generation loves to play pokerJustin PetersBefore this year, my only experience with poker was at basketball camp when I was 12
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