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The pharmaceuucal industry had hoped, in backing the Medicare drug bill, to crush calls for reimportation of U
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rSBA showed no change in either the fluorescence emission profile or the secondary CD profile
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Being at the noncanonical interface, these glycans must be profoundly involved in holding the tetrameric structure rather than being involved in the folding of individual monomeric unit
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With the exception of TAKA and PPA qualitatively a similar behavior was observed for the other α-amylases, namely for BLA and BSUA (Fig
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As this is not available one can at best calculate the minimum average number of binding sites per macromolecule, n, by assuming the maximum fluorescence intensity increment, ~110-fold, ever observed between free and protein-bound ANS (φ^sub Fprotein^/φ^sub Fice^ = 0
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The activity of the inhibited batch was Wild-type DmAChE was expressed in the baculovirus system (38)
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Sodium and ouabain induce proliferation of rat thymic lymphocytes via calcium- and magnesium-dependent reactions
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7 a is a pair of such units
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This method was successfully tested for biomolecular simulations of peptide folding (Schäfer et al
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Comparative Biochemistry and Physiology 44A:283-292
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Individual hands in a block were designated randomly as winning or losing
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Because people play these games with comparatively little computational effort, it is difficult to believe that these players are performing such complex simulations and calculations in real time before making each bet
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Factors influencing wagers in simulated blackjack
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- All this might be less disturbing had Carter confined his post-presidential efforts to such good works as vanquishing the guinea worm
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. A minimum estimate of the anisotropy of 1
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.The three probes which show increased fluorescence in correlation to the TTR misfolding reaction reveal a fluorescence signal during binding to different species
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. Once protein unfolding reached completion in the first jump, the sample was cooled and incubated at 25°C for 1000 s, which was sufficient for completion of the helical refolding (as indicated by flattening of the Θ^sub 222^(t)) but not for the disk reconstitution (as indicated by DSC, EM, and gel electrophoresis)
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. When attempting to elucidate a plausible mechanism of formation of these early, yet relatively thick fibrils, it must be taken into account that the fibrils' ends are not frayed, i
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.CONSEQUENCES OF HIGH-DIMENSIONAL SEARCHESWe have identified two general predictions of this high-dimensional view of folding: 1), the sequential diffusive exploration of low-dimensional subspaces favored by fast folding; and 2), the suggestive stabilization of these subspaces by discriminate but nonnative (or near-native) interactions, without recourse to long-range guiding forces
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.ResultsOvarian developmentBlack rockfish off Oregon exhibited group-synchronous oocyte development; and females extruded only one brood of larvae per year (Fig
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