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This could be due to the fact that CD is reporting global changes in the secondary structure, and fluorescence is monitoring the changes in tertiary structure around fluorescent residues exchange information link phentermine .
The N-terminal domain showed basically the same structure as the EIN^sup ec^ (8,9), since the alignments for homology modeling showed only minor deletions in loops between α-helix I and α-helix 2, α-helix 2 and α-helix 3, and α-helix 3 and α-helix 4 (Fig exchange information link phentermine .
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That a two-contribution model is needed follows from a comparison of average experimental and theoretical R^sub 1^ values exchange information link phentermine .
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