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. It provides an extensive discussion of the gender-related issues, but it does so at the expense of including more detailed information about the pharmacokinetic and pharmacodynamic problems with which this line of research is grappling
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. The curves from the diluted solution (data not shown) were similar to those presented in Figs
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. The precipitate was collected this time by centrifugation at 8000 rpm for 45 min
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. 10 are best explained in terms of distributions tor interatomic distances
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. These results would make sense if denatured-state topologies were equivalent and invariant with sequence
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. The conformational stability and structure of the EI from Streptomyces coelicolor, EI^sup SC^, were explored in the absence and in the presence of its effectors by using several biophysical probes (namely, fluorescence, far-ultraviolet circular dichroism, Fourier transform infrared spectroscopy (FTIR), and differential scanning calorimetry) and computational approaches
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. For thermal and GndHCl-induced unfolded states of BLA, BAA, and of BSUA we made an attempt to initiate a potential refolding process
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. The Early Development of Xenopus laevis: An Atlas of the Histology
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. 1 B, open squares), the protein undergoing this transition must be lipidated
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. Put another way, the vast majority of the space covered by the energy landscape must actually be flat (on a scale of k^sub B^T) rather than funneled
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. , 1998; van Gunsteren et al
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. The RNA strands were deprolected, purified by denaturing urea gel elcctrophoresis, desalted and subsequently purified by reversed-phase high-performance liquid chromatography utilizing an eluent system of acetonitrile and aqueous triethylammonium acetate (100 mM, pH 7)
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. Evidence for a unique folding intermediate in the 4WJ ribozymeOur results indicate that the SL 4WJ ribozyme can fold into a compact conformation in the presence of high Mg^sup 2+^ concentrations, with arms A and B juxtaposed in a similar fashion to the docked native 4WJ ribozyme
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. Appropriate blocking steps were included for endogenous peroxide
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