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5 M denaturant concentration also exibits a loss in the value of the mean residue ellipticity, suggesting that there is a loss in the secondary structure of the protein (Fig
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It is apparent that the role of glycosylation in maintaining conformational stability is more pronounced compared to regulating the ultimate functional form of the protein
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For each amino acid sequence, the form factor was calculated for each snapshot generated from the Monte Carlo simulations
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In EI^sup sc^ at low pH, the fluorescence intensity of ANS was largely enhanced, and the maximum wavelength of the fluorescence spectrum was 480 nm (Fig
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2 C and 3 A) (Table 3)
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The obtained peak maxima around 336-338 nm indicate rather small red shifts (~2-3 nm) with respect to the native state (see also Fitter and Haber-Pohlmeier (14))
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93 [Angstrom]^sup -1^) at the Institute Laue Langevin
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The effects of glycosylation, oligomeric state and differences in catalytic activity on molecular dynamics: AChE versus BChEGlycosylation appears to play a role in prolonging the circulatory lifetime of BChE and AChE (60,61), although it is not required for enzymatic activity
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Notably, this solution is completely transparent compared to when native TTR is incubated under more mild conditions such as pH 4
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In apoA-2:DMPC complexes, the repeatability of the high-temperature transition that involves unfolding of lipidated apoA-2 (Fig
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