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To our knowledge, this is the first demonstration of N-glycans affecting protein stability to such a huge extent, except for a report on a fucosylated peptide PMP-C (Pars interecrebralis major peptide C, a 36-residue peptide) blog meridia .
Sequence-specific conformational preferences are restricted to local length scales that span five to nine residues blog meridia .
1 A); however, there were changes in the secondary structure, as reported by CD (Fig blog meridia .
Further, their internal flexibility increases drastically from compact WT and C3A/C26A to the cavity-forming mutants I7S and F110S blog meridia .
Modeling work was also carried out to compare with the experimental results blog meridia .
thanks Japan International Science and Technology Exchange Center for fellowship No blog meridia .
AN EXAMPLE: THREE-HELIX PROTEINSThe three-helix example illustrates our general conclusion that searches within diffusional subspaces in protein folding may be accelerated by local, but not necessarily native, interactions between sections of partially structured chain blog meridia .
The modal number of myomeres (36-38; n=47) in P blog meridia .
Analysis of combined trajectories can yield information on the difference in the conformational spaces visited by the two trajectories, e blog meridia .
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]where AF = absolute fecundity, or the total number of eggs per female; EW = weight of rinsed eggs (or larvae); SS[C blog meridia .
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