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Since, EI^sup SC^ shows a sigmoidal thermal transition at neutral pH akane soma picture .
, limited to the active site), concern low-frequency collective modes below the sensitivity of the technique used and/or present only on a longer timescale (> 1 ns), and not directly related to fast thermal fluctuations akane soma picture .
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RESULTSMeasurement of protein-membrane associations under pressurePrevious studies of model membranes underpressure suggest that the primary effect of pressure is in the compressible hydrocarbon region, and the application of pressure increases the gel to liquid crystal phase transition by a constant that depends primarily on the lipid chains (Li and Kay, 1977) akane soma picture .
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The former may reflect the relative ease with which a smaller protein with fewer lipid-binding helices can dissociate from the disk as compared to a larger protein with multiple, possibly cooperative lipid binding sites akane soma picture .
1 C) is invariant in repetitive CD and DSC scans (curves 2-4, Fig akane soma picture .
5; and the bridging sheet (code: bridge) and the V3 loop (code: V3) of gp120; see Fig akane soma picture .
) Miner ME, Cabrera JA, Ford E, et al akane soma picture .
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