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. Although R^sub g^ scales with chain length as N^sup 0
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. RESULTSThe compaction of giant T4 DNA in PEG-salt systems was monitored by fluorescent microscopy at the level of single DNA chains
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. In comparison, the misfolded aggregated states from A-state TTR show a much stronger quantum yield for Bis-ANS than for ANS (Fig
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. This apparent K^sub d^, which reflects protein-protein associations on a confined membrane surface, is predicted to be ~2 orders of magnitude weaker when the proteins are free to associate in solution (see Runnels and Scarlata, 1999)
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. Because of the similar donor-acceptor distances in the quasi-docked and specifically-docked conformations, it is difficult to distinguish these two species simply on the basis of the overall FRET efficiency
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