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In EI^sup ec^, the thermal midpoint of the transition monitored by fluorescence is concentration-dependent (52), but the slopes of the native baseline are smaller due to the fact that two tryptophan residues are observed in the C-terminus of EI^sup ec^
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DISCUSSION Subcellular spectroscopy The negligible lipid signal in the spectrum obtained from the voxel in the nucleus demonstrates that although localization errors are not entirely evitable in high-field MRS, there is no significant signal spillover from the surrounding lipid-rich cytoplasm
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Seung-Cheol Lee, Jee-Hyun Cho, and Daniel Mietchen contributed equally to this work
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Thus, (τ^sup o^^sub m^)^sub app^ contains information about the orientation of the N-H^sup N^ bond vector via the angle Φ
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It is however known that the infective species include assembled prion protein (PrP) oligomers in an aberrant folded state called PrP^sup SC^
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6 d, the end of one thread (indicated by the blue circle) seems to grow out of the image's plane facing vertically upwards and making the subfibrils interior penetrable to the AFM tip
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Folding of single-loop ribozyme constructsThe results described in the preceding section suggest that Mg^sup 2+^-induced conformational changes within the helical junction region may control the approach of loops A and B during ribozyme folding
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