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First, small values of H lend robustness in that our results do not become overly sensitive to the specific choices for values of σ^sub ij^
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This is particularly intriguing, since its three-dimensional structure reveals that the active site of AChE, which, like other serine hydrolases, features a Ser-His-Glu catalytic triad, is buried at the bottom of a deep and narrow gorge lined by aromatic residues (26)
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Wetting and Reaction of Sn-2
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TheoryThe equations for the relaxation of a backbone amide ^sup 15^N spin in a protein as well as their interpretation in terms of the model-free approach of Lipari and Szabo (25) are well described in the literature (see, e
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We have found that the emission intensity of labeled coumarin-PLCβ and coumarin-Gβγ showed a substantial and reproducible increase upon the addition of its unlabeled partner, which gives apparent K^sub d^ values similar to those obtained using FRET (Guo et al
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5 min, 1 min, 5 min, 10 min, 20 min, 30 min, 1 h, 24 h, and 1 week
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In the vicinity of the fibers of such chained appearance, there are single amyloid stretches of 155 ± 5 nm length, which is an excellent match with the chain unit's size
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, in the Journal of Nutrition ("The Emerging Role of Dairy Proteins and Bioactive Peptides in Nutrition and Health," vol
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For a moderate system size such as the entire CD4-D1 domain with 1021 atoms, convergence of conformational entropy of both the free and bound states is only observed in the later stage of the 8-ns trajectory segments
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However, when a polymer-solvent system undergoes LLPS prior to crystallization in a certain range of polymer concentration (see Figure 1), the crystallization curve is modified
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