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Biologists today endorse two principal but competing hypotheses to account for the evolution of degenerated eyes
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As for specific predictions, a polymer in the EV limit is best described in terms of two distinct length scales (39)
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These interactions will be determined by the specific sequence or, more precisely, by native-state topology
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Principles of protein folding, misfolding, and aggregation
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Steady-state intrinsic fluorescence Protein samples were excited at 280 and 295 nm between pH 2-12
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The models were constructed with the SWISS MODEL server (33) by using the structures of EIN^sup ec^ (PDB accession code IZYM) and EIC^sup tt^ (PDB accession code 2BG5) as templates
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Thermodynamic and folding properties versus structure among the members of a protein family Early studies suggested that folding and equilibrium pathways of homologous proteins were similar, and that the folding of a certain structure was thus conserved through evolution (58,59)
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The catalytic turnover number of ChEs is among the highest known, approaching the diffusion limit (25)
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Three probes-ANS, DCVJ, and ThT-show increased fluorescence throughout the aggregation reaction, whereas Bis-ANS shows fluorescence decay (Fig
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When comparing ThT and DCVJ fluorescence data from a protofibrillar sample of TTR (24 h incubation), it is evident that DCVJ shows pHindependent fluorescence (Fig
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Suzanne ScarlataDepartment of Physiology & Biophysics, State University of New York at Stony Brook, New York 11794-8661Submitted November 4, 2004, and accepted for publication January 18, 2005
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Differential light scattering and absorption flattening optical effects are minimal in the circular dichroism spectra of small unilameHar vesicles
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The "diffusion-collision" approach, on the other hand, is supported by strong experimental evidence that folding rates are controlled by the rate of diffusion of pieces of the open coil in their search for favorable contacts, rather than a driven collapse along some continuous energy surface (Jacob et al
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[FIGURE 6 OMITTED]DiscussionLiterature describing the early stages of species belonging to the family Pinguipedidae (formerly Mugiloididae) is scarce
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It is fascinating to think that nature custom-made proteins so that, when digested by gut enzymes, useful bioactive peptides result
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Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis
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) Harris W, Luterman A, Curreri PW
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Special authority differs from RP, however, in that Pharmacare will not reimburse any of the cost of targeted drugs for patients who fail to receive prior approval
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This area, like the estimation of the effect of RP on drug prices, remains an area for future research
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The bar graph above illustrates abuse among teens of five different prescription drugs
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Journal of Nursing Education
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Probabilistic TheoriesProbabilistic theories of choice are based on weighted value models that take probabilities of future events into account
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On the psychology of prediction: Whose is the fallacy? Cognition, 7, 385-407
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