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8 a, almost all the sugar residues of the oligomannose chain are involved in a number of interactions with the protein residues, except for residues 4-6 (according to the numbering in Fig addiction story ultram .
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ANS binds to a small extent to the unfolded monomeric form of TTR (Table 2), providing an excellent reference point for molecular dynamics studies of the quaternary structure of TTR addiction story ultram .
For this, the atom-positional least-squares fitting of trajectory structures was performed using backbone atoms (N, Cα, and C') of the individual residues to exclude from the entropy contributions of collective motions of larger structural segments addiction story ultram .
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