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The question we ask is, what is the probability that a sphere of radius a placed at random with respect to the center of mass of the chain will be empty? For each conformation in the EV-limit ensemble, we place a probe sphere of radius a at several random locations with respect to the center of mass and quantity the number of times a chain atom crosses the probe sphere
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The CaM dimer is created by the tip of the N-terminal domain of one CaM monomer contacting the tip of the C-terminal domain of the other CaM
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Salt-induced association of beta-lactoglobulin by light and x-ray scattering
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As both the sensitivity and time-resolution of kinetic experiments increases, finer details of the intermediate diffusional subspaces in this and other proteins should become equally transparent
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Time-resolved FRET (trFRET) measurements were subsequently used to resolve and quantify the equilibrium distribution of extended and docked ribozyme conformers (N
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The resulting histogram can directly reveal conformational subpopulations that are averaged in conventional ensemble FRET measurements
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