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The destabilization of the soman-bound unfolded state is, therefore, likely to arise from a decrease in its entropy, as a consequence of certain configurations no longer being available to the unfolded structure due to the presence of the covalently bound inhibitor
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A dependence on the number of the glycosylation sites was found for only a small percentage of the exchangeable amide H-atoms (65), the exchange rate decreasing with increasing glycosylation
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Addition of 100 mM NaCl to the acid unfolded TTR monomers will immediately shield the positive charges and initiate a conformational change into a so-called A-state (Lai et al
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1 B and by their independence of the scan rate), the heating and cooling curves of the apoA-2:DMPC complexes show hysteresis that was also observed in DMPC complexes with apoC-1 (Gursky et al
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Comparison of the configurational entropies of gp120 and the CD4 D1 domain (denoted CD4 for simplicity in the following) in the free and bound states suggests that the formation of intermolecular hydrogen bonds and hydrophobic contacts contributes most to the entropy changes
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The neighboring residue Q40, which lies at the center of the complex interface, shows the largest reduction among all residues (top row in Fig
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In contrast, the EVA and IPP toners consist of irregular sphere-like particles (Figures 6 and 7)
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One of these pellets (catalogue USNM 601957) is unusual because it contains a large (> 190 mm long when extended), complete primary (P-9) feather (Fig
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