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. For comparison, the δ values calculated from native structures are also shown as open circles
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. How the dilatation symmetry of denatured states is broken under folding conditions will depend on a variety of factors including local biases for turns and short stretches of extended or helical conformations, the drive to sequester hydrophohic amino acids, and the achievement of specificity in side-chain packing (103)
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. A summary of our results from analysis of EV-limit ensembles for 23 different two-state proteins is provided below: 1
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. Scaling behavior and structure of denatured proteins
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